Crash: Mind Over Mutant

Crash: Mind over Mutant is a video game that serves as the direct sequel to Crash of the Titans. It had a multi-platform release for the PlayStation 2, Xbox 360, Wii, and PlayStation Portable. The game was developed by Radical Entertainment and published by Activision in October 2008. The PlayStation Portable port was done by Virtuos. There is also a Nintendo DS version, which was separately developed by TOSE. It, like the Game Boy Advance version of Crash of the Titans, is featured in 2D instead of 3D. Like Crash of the Titans, the game was never released in Japan.

Crash: Mind over Mutants shares its gameplay style with Crash of the Titans. The game introduces a feature allowing a Titan to be stored for later use.

Story
Neo Cortex reunites with N. Brio to create a device named NV that brainwashes any individual who wears it. Coco and Crunch fall victim to Cortex and Brio's mind control, and Crash goes on a journey to save them.